Intratumoural Heterogeneity Underlies Distinct Therapy Responses and Treatment Resistance in Glioblastoma

Glioblastomas are the most common and lethal neoplasms of the central nervous system. Neighbouring glioma cells maintain extreme degrees of genetic and phenotypic variation that form intratumoural heterogeneity. This genetic diversity allows the most adaptive tumour clones to develop treatment resis...

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Detalles Bibliográficos
Autores principales: Akgül, Seçkin, Patch, Ann-Marie, D’Souza, Rochelle C.J., Mukhopadhyay, Pamela, Nones, Katia, Kempe, Sarah, Kazakoff, Stephen H., Jeffree, Rosalind L., Stringer, Brett W., Pearson, John V., Waddell, Nicola, Day, Bryan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406894/
https://www.ncbi.nlm.nih.gov/pubmed/30736342
http://dx.doi.org/10.3390/cancers11020190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406894/
https://www.ncbi.nlm.nih.gov/pubmed/30736342
http://dx.doi.org/10.3390/cancers11020190

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