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SYK Inhibition Potentiates the Effect of Chemotherapeutic Drugs on Neuroblastoma Cells In Vitro

Neuroblastoma is a malignancy arising from the developing sympathetic nervous system and the most common and deadly cancer of infancy. New therapies are needed to improve the prognosis for high-risk patients and to reduce toxicity and late effects. Spleen tyrosine kinase (SYK) has previously been id...

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Detalles Bibliográficos
Autores principales: Tümmler, Conny, Dumitriu, Gianina, Wickström, Malin, Coopman, Peter, Valkov, Andrey, Kogner, Per, Johnsen, John Inge, Moens, Ugo, Sveinbjörnsson, Baldur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406899/
https://www.ncbi.nlm.nih.gov/pubmed/30744170
http://dx.doi.org/10.3390/cancers11020202