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Histone Modifications and the Maintenance of Telomere Integrity

Telomeres, the nucleoprotein structures at the ends of eukaryotic chromosomes, play an integral role in protecting linear DNA from degradation. Dysregulation of telomeres can result in genomic instability and has been implicated in increased rates of cellular senescence and many diseases, including...

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Detalles Bibliográficos
Autores principales: Jezek, Meagan, Green, Erin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407025/
https://www.ncbi.nlm.nih.gov/pubmed/30823596
http://dx.doi.org/10.3390/cells8020199