Cadherin 11 Inhibition Downregulates β-catenin, Deactivates the Canonical WNT Signalling Pathway and Suppresses the Cancer Stem Cell-Like Phenotype of Triple Negative Breast Cancer

Background: Cancer stem cells (CSCs) promote tumor progression and distant metastasis in breast cancer. Cadherin 11 (CDH11) is overexpressed in invasive breast cancer cells and implicated in distant bone metastases in several cancers. The WNT signalling pathway regulates CSC activity. Growing eviden...

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Detalles Bibliográficos
Autores principales: Satriyo, Pamungkas Bagus, Bamodu, Oluwaseun Adebayo, Chen, Jia-Hong, Aryandono, Teguh, Haryana, Sofia Mubarika, Yeh, Chi-Tai, Chao, Tsu-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407101/
https://www.ncbi.nlm.nih.gov/pubmed/30691241
http://dx.doi.org/10.3390/jcm8020148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407101/
https://www.ncbi.nlm.nih.gov/pubmed/30691241
http://dx.doi.org/10.3390/jcm8020148

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