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Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration

BACKGROUND: The administration of certain cannabinoids provides neuroprotection in models of neurodegenerative diseases by acting through various cellular and molecular mechanisms. Many cannabinoid actions in the nervous system are mediated by CB(1) receptors, which can elicit psychotropic effects,...

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Detalles Bibliográficos
Autores principales: Aguareles, José, Paraíso-Luna, Juan, Palomares, Belén, Bajo-Grañeras, Raquel, Navarrete, Carmen, Ruiz-Calvo, Andrea, García-Rincón, Daniel, García-Taboada, Elena, Guzmán, Manuel, Muñoz, Eduardo, Galve-Roperh, Ismael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407204/
https://www.ncbi.nlm.nih.gov/pubmed/30899454
http://dx.doi.org/10.1186/s40035-019-0148-x