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Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration
BACKGROUND: The administration of certain cannabinoids provides neuroprotection in models of neurodegenerative diseases by acting through various cellular and molecular mechanisms. Many cannabinoid actions in the nervous system are mediated by CB(1) receptors, which can elicit psychotropic effects,...
Autores principales: | Aguareles, José, Paraíso-Luna, Juan, Palomares, Belén, Bajo-Grañeras, Raquel, Navarrete, Carmen, Ruiz-Calvo, Andrea, García-Rincón, Daniel, García-Taboada, Elena, Guzmán, Manuel, Muñoz, Eduardo, Galve-Roperh, Ismael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407204/ https://www.ncbi.nlm.nih.gov/pubmed/30899454 http://dx.doi.org/10.1186/s40035-019-0148-x |
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