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PPARγ activation serves as therapeutic strategy against bladder cancer via inhibiting PI3K-Akt signaling pathway

BACKGROUND: Heterogeneity in bladder cancer results in variable clinical outcomes, posing challenges for clinical management of this malignancy. Recent studies suggest both tumor suppressive and oncogenic role of PPARγ in bladder cancer. The fuction of PPARγ signaling pathway in modulating carcinoge...

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Detalles Bibliográficos
Autores principales: Lv, Shidong, Wang, Wei, Wang, Hongyi, Zhu, Yongtong, Lei, Chengyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407222/
https://www.ncbi.nlm.nih.gov/pubmed/30845932
http://dx.doi.org/10.1186/s12885-019-5426-6