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Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer
BACKGROUND: Epigenetic alternation is a common contributing factor to neoplastic transformation. Although previous studies have reported a cluster of aberrant promoter methylation changes associated with silencing of tumor suppressor genes, little is known concerning their sequential DNA methylation...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407227/ https://www.ncbi.nlm.nih.gov/pubmed/30846004 http://dx.doi.org/10.1186/s13148-019-0628-y |