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Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer

BACKGROUND: Epigenetic alternation is a common contributing factor to neoplastic transformation. Although previous studies have reported a cluster of aberrant promoter methylation changes associated with silencing of tumor suppressor genes, little is known concerning their sequential DNA methylation...

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Detalles Bibliográficos
Autores principales: Gu, Simeng, Lin, Shujuan, Ye, Ding, Qian, Sangni, Jiang, Danjie, Zhang, Xiaocong, Li, Qilong, Yang, Jinhua, Ying, Xiaojiang, Li, Zhenjun, Tang, Mengling, Wang, Jianbing, Jin, Mingjuan, Chen, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407227/
https://www.ncbi.nlm.nih.gov/pubmed/30846004
http://dx.doi.org/10.1186/s13148-019-0628-y