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GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

BACKGROUND: Triple-negative breast cancers (TNBCs), which lack receptors for estrogen, progesterone, and amplification of epidermal growth factor receptor 2, are highly aggressive. Consequently, patients diagnosed with TNBCs have reduced overall and disease-free survival rates compared to patients w...

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Detalles Bibliográficos
Autores principales: Vijay, Geraldine Vidhya, Zhao, Na, Den Hollander, Petra, Toneff, Mike J., Joseph, Robiya, Pietila, Mika, Taube, Joseph H., Sarkar, Tapasree R., Ramirez-Pena, Esmeralda, Werden, Steven J., Shariati, Maryam, Gao, Ruli, Sobieski, Mary, Stephan, Clifford C., Sphyris, Nathalie, Miura, Noayuki, Davies, Peter, Chang, Jeffrey T., Soundararajan, Rama, Rosen, Jeffrey M., Mani, Sendurai A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407242/
https://www.ncbi.nlm.nih.gov/pubmed/30845991
http://dx.doi.org/10.1186/s13058-019-1125-0