Probabilistic ancestry maps: a method to assess and visualize population substructures in genetics

BACKGROUND: Principal component analysis (PCA) is a standard method to correct for population stratification in ancestry-specific genome-wide association studies (GWASs) and is used to cluster individuals by ancestry. Using the 1000 genomes project data, we examine how non-linear dimensionality redu...

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Detalles Bibliográficos
Autores principales: Gaspar, Héléna A., Breen, Gerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407257/
https://www.ncbi.nlm.nih.gov/pubmed/30845922
http://dx.doi.org/10.1186/s12859-019-2680-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407257/
https://www.ncbi.nlm.nih.gov/pubmed/30845922
http://dx.doi.org/10.1186/s12859-019-2680-1

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