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Probabilistic ancestry maps: a method to assess and visualize population substructures in genetics
BACKGROUND: Principal component analysis (PCA) is a standard method to correct for population stratification in ancestry-specific genome-wide association studies (GWASs) and is used to cluster individuals by ancestry. Using the 1000 genomes project data, we examine how non-linear dimensionality redu...
Autores principales: | Gaspar, Héléna A., Breen, Gerome |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407257/ https://www.ncbi.nlm.nih.gov/pubmed/30845922 http://dx.doi.org/10.1186/s12859-019-2680-1 |
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