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K13-propeller gene polymorphisms in Plasmodium falciparum parasite population in malaria affected countries: a systematic review of prevalence and risk factors

BACKGROUND: Efficacy of artemisinin (ART) agents, a critical element of current malaria control efforts is threatened by emergence and spread of resistance. Mutations in pfkelch13 gene associated with ART-resistance evolved in Southeast Asia (SEA). k13 mutations whose role in ART-resistance remains...

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Detalles Bibliográficos
Autores principales: Ocan, Moses, Akena, Dickens, Nsobya, Sam, Kamya, Moses R., Senono, Richard, Kinengyere, Alison Annet, Obuku, Ekwaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407282/
https://www.ncbi.nlm.nih.gov/pubmed/30846002
http://dx.doi.org/10.1186/s12936-019-2701-6