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Friend and foe: β-cell Ca(2+) signaling and the development of diabetes
BACKGROUND: The divalent cation Calcium (Ca(2+)) regulates a wide range of processes in disparate cell types. Within insulin-producing β-cells, increases in cytosolic Ca(2+) directly stimulate insulin vesicle exocytosis, but also initiate multiple signaling pathways. Mediated through activation of d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407368/ https://www.ncbi.nlm.nih.gov/pubmed/30630689 http://dx.doi.org/10.1016/j.molmet.2018.12.007 |