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Synthesis and biological evaluation of ursolic acid derivatives bearing triazole moieties as potential anti-Toxoplasma gondii agents

Ursolic acid (UA), a plant-derived compound, has many properties beneficial to health. In the present study, we synthesised three series of novel UA derivatives and evaluated their anti-Toxoplasma gondii activity both in vitro and in vivo. Most derivatives exhibited an improved anti-T. gondii activi...

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Detalles Bibliográficos
Autores principales: Luan, Tian, Jin, Chunmei, Jin, Chun-Mei, Gong, Guo-Hua, Quan, Zhe-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407578/
https://www.ncbi.nlm.nih.gov/pubmed/30836795
http://dx.doi.org/10.1080/14756366.2019.1584622