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Novel Re(I) tricarbonyl coordination compounds based on 2-pyridyl-1,2,3-triazole derivatives bearing a 4-amino-substituted benzenesulfonamide arm: synthesis, crystal structure, computational studies and inhibitory activity against carbonic anhydrase I, II, and IX isoforms†

In this work, two bidentate 2-pyridyl-1,2,3-triazole ligands (3a and 3b) containing a 4-substituted benzenesulfonamide pharmacophore prepared by classical click chemistry procedures, as well as their corresponding rhenium complexes, 4a and 4b of general formula [ReCl(CO)(3)(L)] (L = 3a or 3b) were p...

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Detalles Bibliográficos
Autores principales: Aimene, Yassine, Eychenne, Romain, Mallet-Ladeira, Sonia, Saffon, Nathalie, Winum, Jean-Yves, Nocentini, Alessio, Supuran, Claudiu T., Benoist, Eric, Seridi, Achour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407592/
https://www.ncbi.nlm.nih.gov/pubmed/30843736
http://dx.doi.org/10.1080/14756366.2019.1585835