Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase

Fourteen polyamine analogues, asymmetric or symmetric substituted spermine (1–9) or methoctramine (10–14) analogues, were evaluated as potential inhibitors or substrates of two enzymes of the polyamine catabolic pathway, spermine oxidase (SMOX) and acetylpolyamine oxidase (PAOX). Compound 2 turned o...

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Detalles Bibliográficos
Autores principales: Di Paolo, Maria Luisa, Cervelli, Manuela, Mariottini, Paolo, Leonetti, Alessia, Polticelli, Fabio, Rosini, Michela, Milelli, Andrea, Basagni, Filippo, Venerando, Rina, Agostinelli, Enzo, Minarini, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407594/
https://www.ncbi.nlm.nih.gov/pubmed/30829081
http://dx.doi.org/10.1080/14756366.2019.1584620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407594/
https://www.ncbi.nlm.nih.gov/pubmed/30829081
http://dx.doi.org/10.1080/14756366.2019.1584620

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