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Design of novel proliposome formulation for antioxidant peptide, glutathione with enhanced oral bioavailability and stability

To develop proliposome formulations to improve the oral bioavailability of l-glutathione (GSH), GSH-loaded proliposomes were prepared using the granule method. Mannitol was selected as an effective excipient to achieve the desired particle size, entrapment efficiency (EE), and solubility for oral de...

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Detalles Bibliográficos
Autores principales: Byeon, Jong Chan, Lee, Sang-Eun, Kim, Tae-Hyeon, Ahn, Jung Bin, Kim, Dong-Hyun, Choi, Jin-Seok, Park, Jeong-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407602/
https://www.ncbi.nlm.nih.gov/pubmed/30843439
http://dx.doi.org/10.1080/10717544.2018.1551441