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Dynamic L-type Ca(V)1.2 channel trafficking facilitates Ca(V)1.2 clustering and cooperative gating

L-type Ca(V)1.2 channels are key regulators of gene expression, cell excitability and muscle contraction. Ca(V)1.2 channels organize in clusters throughout the plasma membrane. This channel organization has been suggested to contribute to the concerted activation of adjacent Ca(V)1.2 channels (e.g....

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Detalles Bibliográficos
Autores principales: Ghosh, Debapriya, Nieves-Cintrón, Madeline, Tajada, Sendoa, Brust-Mascher, Ingrid, Horne, Mary C., Hell, Johannes W., Dixon, Rose E., Santana, Luis F., Navedo, Manuel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407617/
https://www.ncbi.nlm.nih.gov/pubmed/29959960
http://dx.doi.org/10.1016/j.bbamcr.2018.06.013