The X-linked tumor suppressor TSPX downregulates cancer-drivers/oncogenes in prostate cancer in a C-terminal acidic domain dependent manner

TSPX is a tumor suppressor gene located at Xp11.22, a prostate cancer susceptibility locus. It is ubiquitously expressed in most tissues but frequently downregulated in various cancers, including lung, brain, liver and prostate cancers. The C-terminal acidic domain (CAD) of TSPX is crucial for the t...

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Detalles Bibliográficos
Autores principales: Kido, Tatsuo, Li, Yunmin, Tanaka, Yuichiro, Dahiya, Rajvir, Chris Lau, Yun-Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407674/
https://www.ncbi.nlm.nih.gov/pubmed/30863497
http://dx.doi.org/10.18632/oncotarget.26673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407674/
https://www.ncbi.nlm.nih.gov/pubmed/30863497
http://dx.doi.org/10.18632/oncotarget.26673

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