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High-fat diet impacts more changes in beta-cell compared to alpha-cell transcriptome

Characterization of endocrine-cell functions and associated molecular signatures in diabetes is crucial to better understand why and by which mechanisms alpha and beta cells cause and perpetuate metabolic abnormalities. The now recognized role of glucagon in diabetes control is a major incentive to...

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Detalles Bibliográficos
Autores principales: Dusaulcy, Rodolphe, Handgraaf, Sandra, Visentin, Florian, Howald, Cedric, Dermitzakis, Emmanouil T., Philippe, Jacques, Gosmain, Yvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407777/
https://www.ncbi.nlm.nih.gov/pubmed/30849121
http://dx.doi.org/10.1371/journal.pone.0213299