Cargando…

High-fat diet impacts more changes in beta-cell compared to alpha-cell transcriptome

Characterization of endocrine-cell functions and associated molecular signatures in diabetes is crucial to better understand why and by which mechanisms alpha and beta cells cause and perpetuate metabolic abnormalities. The now recognized role of glucagon in diabetes control is a major incentive to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dusaulcy, Rodolphe, Handgraaf, Sandra, Visentin, Florian, Howald, Cedric, Dermitzakis, Emmanouil T., Philippe, Jacques, Gosmain, Yvan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407777/ https://www.ncbi.nlm.nih.gov/pubmed/30849121 http://dx.doi.org/10.1371/journal.pone.0213299

Ejemplares similares

miR-132-3p is a positive regulator of alpha-cell mass and is downregulated in obese hyperglycemic mice
por: Dusaulcy, Rodolphe, et al.
Publicado: (2019)

Angiogenin and Osteoprotegerin are type II muscle specific myokines protecting pancreatic beta-cells against proinflammatory cytokines
por: Rutti, Sabine, et al.
Publicado: (2018)

IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death
por: Rütti, Sabine, et al.
Publicado: (2015)

Sphingosine‐1‐phosphate as a key player of insulin secretion induced by high‐density lipoprotein treatment
por: Brulhart‐Meynet, Marie‐Claude, et al.
Publicado: (2021)

High-Resolution Recording of the Circadian Oscillator in Primary Mouse α- and β-Cell Culture
por: Petrenko, Volodymyr, et al.
Publicado: (2017)

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome
por: Nica, Alexandra C., et al.
Publicado: (2013)

Topologically Heterogeneous Beta Cell Adaptation in Response to High-Fat Diet in Mice
por: Ellenbroek, Johanne H., et al.
Publicado: (2013)

Alpha Helices Are More Robust to Mutations than Beta Strands
por: Abrusán, György, et al.
Publicado: (2016)

Alpha cell regulation of beta cell function
por: Moede, Tilo, et al.
Publicado: (2020)

Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity
por: Panousis, Nikolaos I, et al.
Publicado: (2019)

Menin‐regulated Pbk controls high fat diet‐induced compensatory beta cell proliferation
por: Ma, Jian, et al.
Publicado: (2021)

Diet Diversity Is Associated with Beta but not Alpha Diversity of Pika Gut Microbiota
por: Li, Huan, et al.
Publicado: (2016)

The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells
Publicado: (1990)

Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance
por: Shum, Michael, et al.
Publicado: (2021)

Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets
por: González-Mariscal, Isabel, et al.
Publicado: (2018)

Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface
Publicado: (1991)

An unusual lineage of alpha/beta T cells that contains autoreactive cells
Publicado: (1991)

Oligoclonal repertoire of the CD8 alpha alpha and the CD8 alpha beta TCR-alpha/beta murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells
Publicado: (1994)

Understanding the phenotypic impact of non-coding sequence variation
por: Dermitzakis, Emmanouil
Publicado: (2014)

Alpha-to-beta cell trans-differentiation for treatment of diabetes
por: Saleh, Mohamed, et al.
Publicado: (2021)

Autophagy protects pancreatic beta cell mass and function in the setting of a high-fat and high-glucose diet
por: Sheng, Qingfeng, et al.
Publicado: (2017)

Loss of Caveolin-1 Is Associated with a Decrease in Beta Cell Death in Mice on a High Fat Diet
por: Lillo Urzúa, Paloma, et al.
Publicado: (2020)

Mice Lacking Natural Killer T Cells Are More Susceptible to Metabolic Alterations following High Fat Diet Feeding
por: Martin-Murphy, Brittany V., et al.
Publicado: (2014)

Alpha- and beta-adrenergic mediation of changes in metabolism and Na/K exchange in rat brown fat
Publicado: (1985)

Alpha and Beta Naphthol
Publicado: (1901)

The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin
Publicado: (1990)

New role for alpha cells as a source for new beta cells
por: Watada, Hirotaka
Publicado: (2011)

Alpha-cell paracrine signaling in the regulation of beta-cell insulin secretion
por: Holter, Marlena M., et al.
Publicado: (2022)

The Transcriptome of Equine Peripheral Blood Mononuclear Cells
por: Pacholewska, Alicja, et al.
Publicado: (2015)

Surface expression of only gamma delta and/or alpha beta T cell receptor heterodimers by cells with four (alpha, beta, gamma, delta) functional receptor chains
Publicado: (1988)

The genomic landscape of human cellular circadian variation points to a novel role for the signalosome
por: Gaspar, Ludmila, et al.
Publicado: (2017)

When alpha meets beta, mast cells get hyper
por: Ong, Michelle Shuling, et al.
Publicado: (2019)

The alpha 4 integrin chain is a ligand for alpha 4 beta 7 and alpha 4 beta 1
Publicado: (1995)

Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming human beta cell function
por: Rodriguez-Diaz, Rayner, et al.
Publicado: (2011)

High-fat diet-induced obesity affects alpha 7 nicotine acetylcholine receptor expressions in mouse lung myeloid cells
por: Qi, Yong, et al.
Publicado: (2020)

Individualization of Hematopoietic Stem Cell Transplantation Using Alpha/Beta T-Cell Depletion
por: Rådestad, Emelie, et al.
Publicado: (2019)

ISL1 controls pancreatic alpha cell fate and beta cell maturation
por: Bohuslavova, Romana, et al.
Publicado: (2023)

High-fat diet combined with dextran sulfate sodium failed to induce a more serious NASH phenotype than high-fat diet alone
por: Zhou, Yan, et al.
Publicado: (2022)

Regulation of microRNAs in high-fat diet induced hyperlipidemic hamsters
por: Barbalata, Teodora, et al.
Publicado: (2020)

Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering
Publicado: (1992)

Cannot write session to /tmp/vufind_sessions/sess_l68qro9da1l03mlphe2pa9v0bt