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Islet-cell autoantigen 69 mediates the antihyperalgesic effects of electroacupuncture on inflammatory pain by regulating spinal glutamate receptor subunit 2 phosphorylation through protein interacting with C-kinase 1 in mice

Electroacupuncture (EA) is widely used in clinical settings to reduce inflammatory pain. Islet-cell autoantigen 69 (ICA69) has been reported to regulate long-lasting hyperalgesia in mice. ICA69 knockout led to reduced protein interacting with C-kinase 1 (PICK1) expression and increased glutamate rec...

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Detalles Bibliográficos
Autores principales: Han, Kunyuan, Zhang, Anqi, Mo, Yunchang, Mao, Tingting, Ji, Binbin, Li, Dan, Zhuang, Xiuxiu, Qian, Meizi, Chen, Shuangdong, Wang, Zhen, Wang, Junlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407810/
https://www.ncbi.nlm.nih.gov/pubmed/30699097
http://dx.doi.org/10.1097/j.pain.0000000000001450