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Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response

RATIONALE: Secreted and membrane-bound proteins, which account for 1/3 of all proteins, play critical roles in heart health and disease. The endoplasmic reticulum (ER) is the site for synthesis, folding, and quality control of these proteins. Loss of ER homeostasis and function underlies the pathoge...

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Detalles Bibliográficos
Autores principales: Binder, Pablo, Wang, Shunyao, Radu, Maria, Zin, Min, Collins, Lucy, Khan, Saba, Li, Yatong, Sekeres, Karolina, Humphreys, Neil, Swanton, Eileithyia, Reid, Adam, Pu, Fay, Oceandy, Delvac, Guan, Kaomei, Hille, Susanne S., Frey, Norbert, Müller, Oliver J., Cartwright, Elizabeth J., Chernoff, Jonathan, Wang, Xin, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407830/
https://www.ncbi.nlm.nih.gov/pubmed/30620686
http://dx.doi.org/10.1161/CIRCRESAHA.118.312829