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Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response
RATIONALE: Secreted and membrane-bound proteins, which account for 1/3 of all proteins, play critical roles in heart health and disease. The endoplasmic reticulum (ER) is the site for synthesis, folding, and quality control of these proteins. Loss of ER homeostasis and function underlies the pathoge...
Autores principales: | Binder, Pablo, Wang, Shunyao, Radu, Maria, Zin, Min, Collins, Lucy, Khan, Saba, Li, Yatong, Sekeres, Karolina, Humphreys, Neil, Swanton, Eileithyia, Reid, Adam, Pu, Fay, Oceandy, Delvac, Guan, Kaomei, Hille, Susanne S., Frey, Norbert, Müller, Oliver J., Cartwright, Elizabeth J., Chernoff, Jonathan, Wang, Xin, Liu, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407830/ https://www.ncbi.nlm.nih.gov/pubmed/30620686 http://dx.doi.org/10.1161/CIRCRESAHA.118.312829 |
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