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Macrocyclization of peptidoarylacetamides with self-assembly properties through late-stage palladium-catalyzed C(sp(2))▬H olefination

Peptide macrocycles often display diverse bioactivities and self-assembly properties, which lead to a variety of applications in medicinal and material sciences. Transition metal–catalyzed C▬H activations are emerging strategies for site-selective functionalization of amino acids and peptides, as we...

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Detalles Bibliográficos
Autores principales: Tan, Jiantao, Wu, Jie, Liu, Shu, Yao, Hequan, Wang, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408153/
https://www.ncbi.nlm.nih.gov/pubmed/30873434
http://dx.doi.org/10.1126/sciadv.aaw0323