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Stromal cell-derived factor-1α signals via the endothelium to protect the heart against ischaemia-reperfusion injury

AIMS: The chemokine stromal derived factor-1α (SDF-1α) is known to protect the heart acutely from ischaemia-reperfusion injury via its cognate receptor, CXCR4. However, the timing and cellular location of this effect, remains controversial. METHODS AND RESULTS: Wild type male and female mice were su...

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Detalles Bibliográficos
Autores principales: Bromage, Daniel I., Taferner, Stasa, He, Zhenhe, Ziff, Oliver J., Yellon, Derek M., Davidson, Sean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408335/
https://www.ncbi.nlm.nih.gov/pubmed/30738798
http://dx.doi.org/10.1016/j.yjmcc.2019.02.002