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Neurotrophin receptor tyrosine kinases regulated with near-infrared light

Optical control over the activity of receptor tyrosine kinases (RTKs) provides an efficient way to reversibly and non-invasively map their functions. We combined catalytic domains of Trk (tropomyosin receptor kinase) family of RTKs, naturally activated by neurotrophins, with photosensory core module...

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Detalles Bibliográficos
Autores principales: Leopold, Anna V., Chernov, Konstantin G., Shemetov, Anton A., Verkhusha, Vladislav V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408446/
https://www.ncbi.nlm.nih.gov/pubmed/30850602
http://dx.doi.org/10.1038/s41467-019-08988-3