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Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02

Frontal fibrosing alopecia (FFA) is a recently described inflammatory and scarring type of hair loss affecting almost exclusively women. Despite a dramatic recent increase in incidence the aetiopathogenesis of FFA remains unknown. We undertake genome-wide association studies in females from a UK coh...

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Autores principales: Tziotzios, Christos, Petridis, Christos, Dand, Nick, Ainali, Chrysanthi, Saklatvala, Jake R., Pullabhatla, Venu, Onoufriadis, Alexandros, Pramanik, Rashida, Baudry, David, Lee, Sang Hyuck, Wood, Kristie, Liu, Lu, Seegobin, Seth, Michelotti, Gregory A., Lwin, Su M., Christou, Evangelos A. A., Curtis, Charles J., de Rinaldis, Emanuele, Saxena, Alka, Holmes, Susan, Harries, Matthew, Palamaras, Ioulios, Cunningham, Fiona, Parkins, Gregory, Kaur, Manjit, Farrant, Paul, McDonagh, Andrew, Messenger, Andrew, Jones, Jennifer, Jolliffe, Victoria, Ali, Iaisha, Ardern-Jones, Michael, Mitchell, Charles, Burrows, Nigel, Atkar, Ravinder, Banfield, Cedric, Alexandroff, Anton, Champagne, Caroline, Cooper, Hywel L., Vañó-Galván, Sergio, Molina-Ruiz, Ana Maria, Perez, Nerea Ormaechea, Patel, Girish K., Macbeth, Abby, Page, Melanie, Bryden, Alyson, Mowbray, Megan, Wahie, Shyamal, Armstrong, Keith, Cooke, Nicola, Goodfield, Mark, Man, Irene, de Berker, David, Dunnill, Giles, Takwale, Anita, Rao, Archana, Siah, Tee-Wei, Sinclair, Rodney, Wade, Martin S., Dlova, Ncoza C., Setterfield, Jane, Lewis, Fiona, Bhargava, Kapil, Kirkpatrick, Niall, Estivill, Xavier, Stefanato, Catherine M., Flohr, Carsten, Spector, Timothy, Watt, Fiona M., Smith, Catherine H., Barker, Jonathan N., Fenton, David A., Simpson, Michael A., McGrath, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408457/
https://www.ncbi.nlm.nih.gov/pubmed/30850646
http://dx.doi.org/10.1038/s41467-019-09117-w