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RETRACTED ARTICLE: Intracellular citrate accumulation by oxidized ATM-mediated metabolism reprogramming via PFKP and CS enhances hypoxic breast cancer cell invasion and metastasis

Citrate, a substance being related to de novo fatty acid synthesis and tricarboxylic acid (TCA) cycle, has a pivotal role in cell survival. However, the molecular mechanisms that regulate intracellular citrate in triple-negative breast cancer (TNBC), especially under hypoxic condition, remain poorly...

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Detalles Bibliográficos
Autores principales: Peng, Meixi, Yang, Dan, Hou, Yixuan, Liu, Shuiqing, Zhao, Maojia, Qin, Yilu, Chen, Rui, Teng, Yong, Liu, Manran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408469/
https://www.ncbi.nlm.nih.gov/pubmed/30850587
http://dx.doi.org/10.1038/s41419-019-1475-7