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Germline susceptibility variants impact clinical outcome and therapeutic strategies for stage III colorectal cancer
Although somatic mutations are the main cause of cancer, underlying germline alterations may affect cancer outcome. There is little information on comprehensive analysis of germline genome sequencing for cancer healthcare strategy. Here we studied the implication of germline cancer-associated varian...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408483/ https://www.ncbi.nlm.nih.gov/pubmed/30850667 http://dx.doi.org/10.1038/s41598-019-40571-0 |