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Germline susceptibility variants impact clinical outcome and therapeutic strategies for stage III colorectal cancer

Although somatic mutations are the main cause of cancer, underlying germline alterations may affect cancer outcome. There is little information on comprehensive analysis of germline genome sequencing for cancer healthcare strategy. Here we studied the implication of germline cancer-associated varian...

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Detalles Bibliográficos
Autores principales:	Lin, Peng-Chan, Yeh, Yu-Min, Wu, Pei-Ying, Hsu, Keng-Fu, Chang, Jang-Yang, Shen, Meng-Ru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408483/ https://www.ncbi.nlm.nih.gov/pubmed/30850667 http://dx.doi.org/10.1038/s41598-019-40571-0

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