RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones

We show that transcription induced by nuclear receptors for estrogen (E(2)) or retinoic acid (RA) is associated with formation of chromatin loops that juxtapose the 5’ end (containing the promoter) with the enhancer and the 3′ polyA addition site of the target gene. We find three loop configurations...

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Detalles Bibliográficos
Autores principales: Pezone, Antonio, Zuchegna, Candida, Tramontano, Alfonso, Romano, Antonella, Russo, Giusi, de Rosa, Mariarosaria, Vinciguerra, Maria, Porcellini, Antonio, Gottesman, Max E., Avvedimento, Enrico Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408484/
https://www.ncbi.nlm.nih.gov/pubmed/30850627
http://dx.doi.org/10.1038/s41598-019-40123-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408484/
https://www.ncbi.nlm.nih.gov/pubmed/30850627
http://dx.doi.org/10.1038/s41598-019-40123-6

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