Cargando…
RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones
We show that transcription induced by nuclear receptors for estrogen (E(2)) or retinoic acid (RA) is associated with formation of chromatin loops that juxtapose the 5’ end (containing the promoter) with the enhancer and the 3′ polyA addition site of the target gene. We find three loop configurations...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408484/ https://www.ncbi.nlm.nih.gov/pubmed/30850627 http://dx.doi.org/10.1038/s41598-019-40123-6 |