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HIV infection and latency induce a unique metabolic signature in human macrophages

Currently, a major barrier to curing HIV infection is the generation of tissue-associated, non-replicating, long-lasting viral reservoirs that are refractory to therapy and can be reactivated upon anti-retroviral therapy interruption. One of these reservoirs are latently HIV-infected macrophages. He...

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Detalles Bibliográficos
Autores principales: Castellano, Paul, Prevedel, Lisa, Valdebenito, Silvana, Eugenin, Eliseo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408492/
https://www.ncbi.nlm.nih.gov/pubmed/30850623
http://dx.doi.org/10.1038/s41598-019-39898-5