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Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype

Tumor-immune cell interactions shape the immune cell phenotype, with microRNAs (miRs) being crucial components of this crosstalk. How they are transferred and how they affect their target landscape, especially in tumor-associated macrophages (TAMs), is largely unknown. Here we report that breast can...

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Detalles Bibliográficos
Autores principales: Frank, Ann-Christin, Ebersberger, Stefanie, Fink, Annika F., Lampe, Sebastian, Weigert, Andreas, Schmid, Tobias, Ebersberger, Ingo, Syed, Shahzad Nawaz, Brüne, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408494/
https://www.ncbi.nlm.nih.gov/pubmed/30850595
http://dx.doi.org/10.1038/s41467-019-08989-2