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Cryo-EM structure of the human ferritin–transferrin receptor 1 complex

Human transferrin receptor 1 (CD71) guarantees iron supply by endocytosis upon binding of iron-loaded transferrin and ferritin. Arenaviruses and the malaria parasite exploit CD71 for cell invasion and epitopes on CD71 for interaction with transferrin and pathogenic hosts were identified. Here, we pr...

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Detalles Bibliográficos
Autores principales: Montemiglio, Linda Celeste, Testi, Claudia, Ceci, Pierpaolo, Falvo, Elisabetta, Pitea, Martina, Savino, Carmelinda, Arcovito, Alessandro, Peruzzi, Giovanna, Baiocco, Paola, Mancia, Filippo, Boffi, Alberto, des Georges, Amédée, Vallone, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408514/
https://www.ncbi.nlm.nih.gov/pubmed/30850661
http://dx.doi.org/10.1038/s41467-019-09098-w