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Cryo-EM structure of the human ferritin–transferrin receptor 1 complex
Human transferrin receptor 1 (CD71) guarantees iron supply by endocytosis upon binding of iron-loaded transferrin and ferritin. Arenaviruses and the malaria parasite exploit CD71 for cell invasion and epitopes on CD71 for interaction with transferrin and pathogenic hosts were identified. Here, we pr...
Autores principales: | Montemiglio, Linda Celeste, Testi, Claudia, Ceci, Pierpaolo, Falvo, Elisabetta, Pitea, Martina, Savino, Carmelinda, Arcovito, Alessandro, Peruzzi, Giovanna, Baiocco, Paola, Mancia, Filippo, Boffi, Alberto, des Georges, Amédée, Vallone, Beatrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408514/ https://www.ncbi.nlm.nih.gov/pubmed/30850661 http://dx.doi.org/10.1038/s41467-019-09098-w |
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