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ApoE-fragment/Aβ heteromers in the brain of patients with Alzheimer’s disease

Identification of endogenous pathological amyloid β peptides (Aβ) forms in the brains of patients with Alzheimer’s disease (AD) is still unclear. In healthy brain, Aβ can associate with Apolipoprotein E (ApoE) which is involved in its metabolism and clearance. In the brain of patients with AD, ApoE...

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Detalles Bibliográficos
Autores principales: Mouchard, Amandine, Boutonnet, Marie-Charlotte, Mazzocco, Claire, Biendon, Nathalie, Macrez, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408522/
https://www.ncbi.nlm.nih.gov/pubmed/30850702
http://dx.doi.org/10.1038/s41598-019-40438-4