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Enterovirus particles expel capsid pentamers to enable genome release

Viruses from the genus Enterovirus are important human pathogens. Receptor binding or exposure to acidic pH in endosomes converts enterovirus particles to an activated state that is required for genome release. However, the mechanism of enterovirus uncoating is not well understood. Here, we use cryo...

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Detalles Bibliográficos
Autores principales: Buchta, David, Füzik, Tibor, Hrebík, Dominik, Levdansky, Yevgen, Sukeník, Lukáš, Mukhamedova, Liya, Moravcová, Jana, Vácha, Robert, Plevka, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408523/
https://www.ncbi.nlm.nih.gov/pubmed/30850609
http://dx.doi.org/10.1038/s41467-019-09132-x