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Induction of tumor-specific CTL responses using the C-terminal fragment of Viral protein R as cell penetrating peptide
The discovery of tumor-associated antigens recognized by T lymphocytes opens the possibility of vaccinating cancer patients with defined antigens. However, one of the major limitation of peptide-based vaccines is the low immunogenicity of antigenic peptides. Interestingly, if these epitopes are dire...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408526/ https://www.ncbi.nlm.nih.gov/pubmed/30850685 http://dx.doi.org/10.1038/s41598-019-40594-7 |