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Induction of tumor-specific CTL responses using the C-terminal fragment of Viral protein R as cell penetrating peptide

The discovery of tumor-associated antigens recognized by T lymphocytes opens the possibility of vaccinating cancer patients with defined antigens. However, one of the major limitation of peptide-based vaccines is the low immunogenicity of antigenic peptides. Interestingly, if these epitopes are dire...

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Detalles Bibliográficos
Autores principales: Gross, D. A., Leborgne, C., Chappert, P., Masurier, C., Leboeuf, M., Monteilhet, V., Boutin, S., Lemonnier, F. A., Davoust, J., Kichler, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408526/
https://www.ncbi.nlm.nih.gov/pubmed/30850685
http://dx.doi.org/10.1038/s41598-019-40594-7