Cargando…

LAMB3 mediates apoptotic, proliferative, invasive, and metastatic behaviors in pancreatic cancer by regulating the PI3K/Akt signaling pathway

The poor prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is partially attributed to the invasive and metastatic behavior of this disease. Laminin subunit beta-3 (LAMB3) encodes one of the three subunits of LM-332, an extracellular matrix protein secreted by cultured human keratino...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Hong, Pan, Yao-zhen, Cheung, May, Cao, Mary, Yu, Chao, Chen, Ling, Zhan, Lei, He, Zhi-wei, Sun, Cheng-yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408539/
https://www.ncbi.nlm.nih.gov/pubmed/30850586
http://dx.doi.org/10.1038/s41419-019-1320-z