Targeting c-MET by Tivantinib through synergistic activation of JNK/c-jun pathway in cholangiocarcinoma

Clinical treatment options for human cholangiocarcinoma (CC) are limited. c-MET, a high-affinity receptor for hepatocyte growth factor (HGF), is deregulated in many cancers. Its role in cholangiocarcinogenesis remains unclear. In current study, 23 corresponding tumor- and non-tumor tissues, taken fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Kai, Li, Mao, Zöller, Margot, Wang, Meng, Mehrabi, Arianeb, Hoffmann, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408560/
https://www.ncbi.nlm.nih.gov/pubmed/30850583
http://dx.doi.org/10.1038/s41419-019-1460-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408560/
https://www.ncbi.nlm.nih.gov/pubmed/30850583
http://dx.doi.org/10.1038/s41419-019-1460-1

Ejemplares similares