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Targeting c-MET by Tivantinib through synergistic activation of JNK/c-jun pathway in cholangiocarcinoma
Clinical treatment options for human cholangiocarcinoma (CC) are limited. c-MET, a high-affinity receptor for hepatocyte growth factor (HGF), is deregulated in many cancers. Its role in cholangiocarcinogenesis remains unclear. In current study, 23 corresponding tumor- and non-tumor tissues, taken fr...
Autores principales: | Wei, Kai, Li, Mao, Zöller, Margot, Wang, Meng, Mehrabi, Arianeb, Hoffmann, Katrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408560/ https://www.ncbi.nlm.nih.gov/pubmed/30850583 http://dx.doi.org/10.1038/s41419-019-1460-1 |
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