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Clinico-Haematologic association and prognostic relevance of NPM1 and FLT3-ITD mutations in acute Myeloid Leukaemia

BACKGROUND & OBJECTIVES: Molecular genetic abnormalities have a significant role not only in diagnosis but also in determining the clinical course and prognosis. Nucleophosmin-1 (NPM-1) is associated with good prognosis while internal tandem duplication of the fms-like tyrosine kinase-3 gene (FL...

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Detalles Bibliográficos
Autores principales: Mahmood, Rafia, Altaf, Chaudhry, Malik, Hamid Saeed, Khan, Saleem Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408656/
https://www.ncbi.nlm.nih.gov/pubmed/30881390
http://dx.doi.org/10.12669/pjms.35.1.285