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Elevated doublecortin-like kinase 1 serum levels revert to baseline after therapy in early stage esophageal adenocarcinoma

BACKGROUND: Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) incidence has been increasing in the United States for greater than 30 years. For the majority of EAC patients, treatment is limited and prognosis poor. Doublecortin like kinase-1 (DCLK1) is a cancer stem cell marker with eleva...

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Detalles Bibliográficos
Autores principales: Christman, Emily M., Chandrakesan, Parthasarathy, Weygant, Nathaniel, Maple, John T., Tierney, William M., Vega, Kenneth J., Houchen, Courtney W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408757/
https://www.ncbi.nlm.nih.gov/pubmed/30899515
http://dx.doi.org/10.1186/s40364-019-0157-z