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Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase

BACKGROUND: Current chemotherapy for castration-resistant prostate cancer is established on taxane-based compounds like docetaxel. However, eventually, the development of toxic side effects and resistance limits the therapeutic benefit being the major concern in the treatment of prostate cancer. Com...

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Detalles Bibliográficos
Autores principales: Sánchez, Belén G., Bort, Alicia, Mateos-Gómez, Pedro A., Rodríguez-Henche, Nieves, Díaz-Laviada, Inés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408806/
https://www.ncbi.nlm.nih.gov/pubmed/30899201
http://dx.doi.org/10.1186/s12935-019-0769-2