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The effect of hemorrhagic shock and intraosseous adrenaline injection on the delivery of a subsequently administered drug - an experimental study

BACKGROUND: Intraosseous (IO) access is a recommended method when venous access cannot be rapidly established in an emergency. Experimental data suggest that major hemorrhage and catecholamine administration both reduce bone marrow blood flow. We studied the uptake of gentamicin as a tracer substanc...

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Detalles Bibliográficos
Autores principales: Eriksson, Mats, Larsson, Anders, Lipcsey, Miklós, Strandberg, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408834/
https://www.ncbi.nlm.nih.gov/pubmed/30850019
http://dx.doi.org/10.1186/s13049-018-0569-z