Quantification of intrinsic subtype ambiguity in Luminal A breast cancer and its relationship to clinical outcomes

BACKGROUND: PAM50 gene profiling assigns each cancer to a single intrinsic subtype. However, individual cancers vary in their adherence to a prototype, and due to bulk tissue sampling, some may exhibit expression patterns that indicate intra-tumor admixture of multiple subtypes. Our objective was to...

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Detalles Bibliográficos
Autores principales: Kumar, Neeraj, Zhao, Dan, Bhaumik, Dulal, Sethi, Amit, Gann, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408846/
https://www.ncbi.nlm.nih.gov/pubmed/30849944
http://dx.doi.org/10.1186/s12885-019-5392-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408846/
https://www.ncbi.nlm.nih.gov/pubmed/30849944
http://dx.doi.org/10.1186/s12885-019-5392-z

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