Cargando…

Quantification of intrinsic subtype ambiguity in Luminal A breast cancer and its relationship to clinical outcomes

BACKGROUND: PAM50 gene profiling assigns each cancer to a single intrinsic subtype. However, individual cancers vary in their adherence to a prototype, and due to bulk tissue sampling, some may exhibit expression patterns that indicate intra-tumor admixture of multiple subtypes. Our objective was to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Neeraj, Zhao, Dan, Bhaumik, Dulal, Sethi, Amit, Gann, Peter H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408846/ https://www.ncbi.nlm.nih.gov/pubmed/30849944 http://dx.doi.org/10.1186/s12885-019-5392-z

Ejemplares similares

Quantification of subtype purity in Luminal A breast cancer predicts clinical characteristics and survival
por: Kumar, Neeraj, et al.
Publicado: (2023)

Prognostic parameters of luminal A and luminal B intrinsic breast cancer subtypes of Pakistani patients
por: Hashmi, Atif Ali, et al.
Publicado: (2018)

Proposed new clinicopathological surrogate definitions of luminal A and luminal B (HER2-negative) intrinsic breast cancer subtypes
por: Maisonneuve, Patrick, et al.
Publicado: (2014)

PCA-PAM50 improves consistency between breast cancer intrinsic and clinical subtyping reclassifying a subset of luminal A tumors as luminal B
por: Raj-Kumar, Praveen-Kumar, et al.
Publicado: (2019)

Clinical and prognostic profile of Her2neu positive (non-luminal) intrinsic breast cancer subtype: comparison with Her2neu positive luminal breast cancers
por: Hashmi, Atif Ali, et al.
Publicado: (2018)

Luminal B is the Most Common Intrinsic Molecular Subtypes of Invasive Ductal Breast Carcinoma Patients in East Kalimantan, Indonesia
por: Paramita, Swandari, et al.
Publicado: (2019)

Identification of a Novel Luminal Molecular Subtype of Breast Cancer
por: Dvorkin-Gheva, Anna, et al.
Publicado: (2014)

Ki-67 (30-9) scoring and differentiation of Luminal A- and Luminal B-like breast cancer subtypes
por: Viale, Giuseppe, et al.
Publicado: (2019)

CXCL12 and CXCR4 as Potential Early Biomarkers for Luminal A and Luminal B Subtypes of Breast Cancer
por: Motyka, Joanna, et al.
Publicado: (2023)

Application of DCE-MRI radiomics signature analysis in differentiating molecular subtypes of luminal and non-luminal breast cancer
por: Huang, Ting, et al.
Publicado: (2023)

Association between Obesity, Race or Ethnicity, and Luminal Subtypes of Breast Cancer
por: Menikdiwela, Kalhara R., et al.
Publicado: (2022)

Getting deep in the luminal B breast cancer subtype and its ki67 cut-off value
por: Ciruelos, E, et al.
Publicado: (2011)

Expression of androgen receptor and its regulatory molecule Lin28 in non-luminal subtype breast cancer
por: Sa-Nguanraksa, Doonyapat, et al.
Publicado: (2020)

MRI texture analysis in differentiating luminal A and luminal B breast cancer molecular subtypes - a feasibility study
por: Holli-Helenius, Kirsi, et al.
Publicado: (2017)

A mouse model for Luminal epithelial like ER positive subtype of human breast cancer
por: Kumar, MJ Mahesh, et al.
Publicado: (2007)

Deep Learning to Estimate Human Epidermal Growth Factor Receptor 2 Status from Hematoxylin and Eosin-Stained Breast Tissue Images
por: Anand, Deepak, et al.
Publicado: (2020)

Intrinsic apoptotic pathway activation increases response to anti-estrogens in luminal breast cancers
por: Williams, Michelle M., et al.
Publicado: (2018)

BRIP1 overexpression is correlated with clinical features and survival outcome of luminal breast cancer subtypes
por: Gupta, Ishita, et al.
Publicado: (2017)

Luminal A and luminal B (HER2 negative) subtypes of breast cancer consist of a mixture of tumors with different genotype
por: Yanagawa, Masumi, et al.
Publicado: (2012)

Luminal B breast cancer subtype displays a dicotomic epigenetic pattern
por: Bediaga, Naiara G., et al.
Publicado: (2016)

Characterizing the Relapse Potential in Different Luminal Subtypes of Breast Cancers with Functional Proteomics
por: Lin, Tung-Yi, et al.
Publicado: (2020)

FKBP4 is a malignant indicator in luminal A subtype of breast cancer
por: Xiong, Hanchu, et al.
Publicado: (2020)

Intrinsic subtypes in Ethiopian breast cancer patient
por: Desalegn, Zelalem, et al.
Publicado: (2022)

Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome
por: Aure, Miriam Ragle, et al.
Publicado: (2017)

SUN-122 Nuclear PDCD4 Expression Predicts Good Clinical Outcome in Luminal A-Like and Luminal B-Like Breast Cancer Subtypes
por: Madera, Santiago, et al.
Publicado: (2020)

EpCAM expression varies significantly and is differentially associated with prognosis in the luminal B HER2(+), basal-like, and HER2 intrinsic subtypes of breast cancer
por: Soysal, S D, et al.
Publicado: (2013)

Perceptual inference employs intrinsic alpha frequency to resolve perceptual ambiguity
por: Shen, Lu, et al.
Publicado: (2019)

Association between mammographic density and basal-like and luminal A breast cancer subtypes
por: Razzaghi, Hilda, et al.
Publicado: (2013)

An integrated genomics approach identifies drivers of proliferation in luminal subtype human breast cancer
por: Gatza, Michael L., et al.
Publicado: (2014)

Association Between Insulin Resistance and Luminal B Subtype Breast Cancer in Postmenopausal Women
por: Nam, Sanggeun, et al.
Publicado: (2016)

A high-risk luminal A dominant breast cancer subtype with increased mobility
por: Guo, Liping, et al.
Publicado: (2019)

Potential Benefits of Neoadjuvant Chemotherapy in Clinically Node-Positive Luminal Subtype(−) Breast Cancer
por: Kim, Hyung Suk, et al.
Publicado: (2019)

MCM6 versus Ki-67 in diagnosis of luminal molecular subtypes of breast cancers
por: Sadeghian, Dorsay, et al.
Publicado: (2022)

RNA m(6)A Methylation Regulators Subclassify Luminal Subtype in Breast Cancer
por: Yang, Lin, et al.
Publicado: (2021)

Luminal androgen receptor breast cancer subtype and investigation of the microenvironment and neoadjuvant chemotherapy response
por: Thompson, Kevin J, et al.
Publicado: (2022)

Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype
por: Shao, Fangyuan, et al.
Publicado: (2017)

Ki67 index in intrinsic breast cancer subtypes and its association with prognostic parameters
por: Hashmi, Atif Ali, et al.
Publicado: (2019)

Intrinsic molecular subtypes of HER2+ breast cancer
por: Prat, Aleix, et al.
Publicado: (2017)

Explaining #theShoe based on the optimal color hypothesis: The role of chromaticity vs. luminance distribution in an ambiguous image
por: Morimoto, Takuma, et al.
Publicado: (2021)

Young Age Is Associated with Increased Locoregional Recurrence in Node-Positive Breast Cancer with Luminal Subtypes
por: Kim, Sang-Won, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_rfq3vv4388vbc35h71fjqs1k78